NUTRIXcell Ultra protects boar spermatozoa in case of temperature fluctuation


IMV R&D department developed a biological compound, called Bioactivator, which amplifies the biosynthesis of platelet-activating factors (PAFs). PAFs stimulate the motility of spermatozoa, promote ovum penetration, and ultimately improve fertility. 

In 2018, IMV improved this molecule, newly named Bioactivator Ultra, which has the same properties as Bioactivator, along with a protective role.  

To observe the protection during temperature fluctuations, the spermatozoa were stressed in different types of media during in vitro tests. The following protocol was used:   

  • 3 samples of pooled semen were split and diluted with different media to be able to compare data  
  • The semen was stored in media and a normal cooling process was used down to 17°C. The semen was kept during 12 hours at 17°C.  
  • After this step, the diluted semen was stored at 10°C during 16 hours to simulate what could happen during long transport for example.   
  • After 16 hours, the samples were put back in a fridge at 17°C.  
  • The motility results were controlled at different moments during the test to control the effects of the temperature.

The same protocol was used for other semen samples, which were stressed at 25°C during 16 hours, instead of 10°C.

In this experiment, the result is the same: semen stored in NUTRIXcell Ultra is not impacted by storage during 16 hours at 25°C.

NUTRIXcell Ultra  is a media developed to protect semen quality against environmental stress, such as temperature fluctuations.